Synergy4 Microplate Fluorescence Luminescence Absorbance Reader with fluorescence polarisation and time resolved fluorescence. Monochromator based.

Synergy 4 Multi-detection Microplate Reader

The Synergy™ 4 with Hybrid Technology™ combines two both filter-based and monochromator-based optical systems in one compact unit.This allows complete flexibility and instant control over application choice for both current and future requirements.

Synergy 4 is the world's first true multi-detection system capable of performing an unlimited number of microplate based assays.

Synergy 4 is a five-mode modular microplate reader designed for the life science research and drug discovery fields, providing unprecedented levels of performance. It combines the Performance of filter-based systems with the flexibility and convenience of monochromator-based readers to provide the broadest range of applications available today.

Synergy 4 detection modes and applications include Fluorescence Intensity, Fluorescence Polarization, Time-Resolved Fluorescence, Luminescence, UV-visible Absorbance, FRET, TR-FRET, BRET, well area scanning and Spectral scanning.

With built-in temperature control and user-programmable shaking, plus the option of dual reagent injectors, virtually any microplate based application is possible.

Synergy 4 features include:

Hybrid Technology

Combined filter-based and monochromator-based systems gives the sensitivity of a filter-based instrument with the flexibility of a monochromator-based one.
Modular architecture

Read modes are available as individual modules
Detection modes and applications include:

Screening assays (e.g. fluorescence polarization, TR-FRET, luminescence), AlphaScreen™
Spectral Scanning
Binding assays
Ion channel assays
Quantitative assays (DNA, protein)
Kinetic assays
Gene expression assays (GFP, Luciferase)
ELISA assays
Cell proliferation, cytotoxicity assays

Quadruple Grating System

Two double-grating monochromators produce the very best stray light rejection, continuous selection of both excitation and emission wavelengths and spectral scanning capabilities.

Deep blocking filter and dichroic mirrors

This system provides the best possible performance in fluorescence intensity, time resolved fluorescence and fluorescence polarization measurements.

The Synergy 4 filter/mirror system delivers high levels of energy to the sample and provides high signal-to-noise ratios. Faster read speeds, better sensitivity, more precise control over optical parameters - this system delivers ultimate performance.

Certified by Reagent Kit manufacturers

Certified by Promega for Dual Luciferase Reporter (DLR) gene assay; high performance TRF detection certified by Cisbio for HTRF^® TR-FRET assay platform.